yes — there are plenty of English-translated comics that revolve around infidelity, cheating, and messy adult relationships. Some are officially licensed and sold by mainstream publishers or released on legitimate platforms, and others exist as fan translations. The tone ranges wildly: some works treat betrayal as gritty drama, others use it for soap-opera-level melodrama, and a few are outright erotic. If you search tags like 'mature', 'josei', 'seinen', 'romance', or 'drama' on major sites you'll find a lot.
Official places to check are the big digital storefronts and apps: publisher sites, Kindle/ComiXology, LINE Webtoon,
Tapas, and library apps like Libby/OverDrive. For older or niche titles there are licensed English volumes and occasionally out-of-print books that pop up on secondhand sites. I’ve come across titles like 'Scum's
wish' and 'Domestic Girlfriend' in English, and those give a good sense of how varied the storytelling can be. Just be mindful of content warnings and age gates — some translations are explicit or mature and may be region-locked. Personally, I find the raw emotional nastiness of these stories strangely compelling; they’re messy, but they make for addictive reads.