I think the biggest hurdle is audience expectation. Werecreatures are often coded as rage and savagery, a very masculine archetype of the 'beast' losing control. So a female character embodying that physical, monstrous power can unsettle readers looking for softer fantasy heroines. She’s not a graceful wolf or a mystical fox; a bear is blunt, huge, and earth-shattering. Her challenges would be about commanding that kind of awe without being neutered into a 'softer' creature.
Then there’s the pack hierarchy angle. If she’s an alpha, does her leadership get questioned more because she’s female? Does she have to constantly prove her strength in ways a male alpha wouldn’t? A male werebear might be seen as naturally dominant, but she might face whispers about being 'too emotional' or 'unpredictable'—basically, her bear nature getting blamed on her gender in a nasty double bind.
I’d love to see a story tackle the motherhood angle head-on. A female werebear protecting cubs, or struggling with the instinct to provide and defend a territory versus a desire for something else. That raw, maternal ferocity could be incredible, but it’s rarely explored without making the character solely a mother. She could be a leader, a loner, a warrior, and also have those instincts—they’d add layers, not define her entirely.
Honestly, the challenge is letting her be as messy, violent, solitary, and physically imposing as a male werebear character would be allowed to be, without forcing her into a romance plot to 'tame' her or making her fury a symptom of trauma rather than just part of her nature. Let her enjoy the strength sometimes, you know?